Which site is considered the preferred location for determining fracture prediction?

• A. Distal radius
• B. Proximal femur
• C. Thoracic spine
• D. Humerus

Answer: (B)

The proximal femur is considered the preferred location for determining fracture prediction due to its significant association with osteoporosis-related fractures. This site is crucial because it is one of the most common locations for hip fractures, which have a high morbidity and mortality rate among the elderly population. Densitometry measurements at the proximal femur can provide valuable information regarding bone density and structural integrity, which are critical factors influencing fracture risk.

Additionally, the architecture of the proximal femur plays a vital role in weight-bearing mechanics and balance, making it particularly sensitive to changes in bone density. As such, the results obtained from bone density measurements in this area are typically strong indicators of overall fracture risk. The International Society for Clinical Densitometry and other leading organizations recommend assessing the proximal femur as part of the standard protocol for evaluating osteoporosis and fracture risk assessment.

In contrast, the other sites mentioned, while important for specific contexts, do not carry the same predictive validity for fractures caused by osteoporosis as the proximal femur. For example, the distal radius may provide some information about bone density but does not correlate as directly with hip fracture risk. Similarly, while the thoracic spine can show vertebral fractures, it does not serve as a general predictor for hip fractures. The hum