Which organization developed the FRAX algorithm?

• A. CDC
• B. WHO
• C. NCCN
• D. FDA

Answer: (B)

The FRAX algorithm was developed by the World Health Organization (WHO) as a clinical tool to evaluate the 10-year probability of osteoporotic fractures in individuals. The primary purpose of the FRAX tool is to assist healthcare providers in assessing fracture risk in patients, especially in those who may be candidates for osteoporosis treatment. The algorithm incorporates various clinical risk factors as well as bone mineral density (BMD) measurements, ensuring a comprehensive evaluation that reflects both clinical and pedigree factors.

The development of FRAX by WHO is significant as it highlights a global initiative to standardize fracture risk assessment, making it easier for providers and patients across different regions to utilize a common framework for osteoporosis management. This tool is widely accepted and integrated into guidelines for osteoporosis treatment and prevention, underscoring WHO's commitment to addressing bone health comprehensively on an international scale.

Other organizations such as the CDC, NCCN, and FDA play crucial roles in public health, cancer care, and drug regulation, respectively, but none developed the FRAX algorithm specifically. The focus of the FRAX algorithm on fracture risk assessment distinctly aligns with the objectives of WHO in promoting global health standards, particularly for conditions like osteoporosis.