Which of the following is NOT a factor that affects bone resorption?

• A. Age
• B. Nutrition
• C. Temperature
• D. Hormones

Answer: (C)

Bone resorption is a critical process in maintaining skeletal health, involving the breakdown of bone by cells known as osteoclasts. Several well-established factors influence this process, including age, nutrition, and hormones.

Age plays a significant role in bone resorption. As individuals age, the balance between bone formation and resorption can shift, often leading to an increase in resorption, which can contribute to conditions such as osteoporosis.

Nutrition is also a crucial factor because various nutrients, especially calcium and vitamin D, are essential for bone health. Inadequate nutrition can lead to diminished bone density and increased resorption as the body attempts to maintain calcium levels.

Hormones significantly impact bone metabolism. Specifically, hormones like parathyroid hormone (PTH) and estrogen regulate osteoclast activity, influencing the rate of bone resorption. For example, decreased estrogen after menopause is associated with increased bone resorption and higher fracture risk.

Temperature, on the other hand, is not directly linked to the mechanisms of bone resorption. While it may influence general metabolic processes in the body, it does not have a recognized effect on the cellular activities related to bone breakdown. Therefore, among the listed options, it stands out as unrelated to the process of bone resorption.