Which bisphosphonate can be administered with multiple dosing schedules including daily, weekly, or monthly?

• A. Alendronate
• B. Risedronate
• C. Ibandronate
• D. Zoledronic Acid

Answer: (B)

The bisphosphonate that can be administered with multiple dosing schedules, including daily, weekly, or monthly, is risedronate. This flexible dosing regimen allows for tailored treatment plans that can accommodate patient preferences and adherence. Risedronate is available in various formulations, such as a daily tablet, a weekly tablet, and a monthly tablet, making it easier for patients to follow their prescribed treatment.

In contrast, while other bisphosphonates might have specific dosing schedules, they do not offer the same range of options. For example, alendronate is commonly prescribed as a weekly or daily tablet but does not typically come in a monthly formulation as risedronate does. Ibandronate is primarily available in a monthly oral formulation or as an intravenous injection given every three months. Zoledronic acid is usually administered as an intravenous infusion annually for osteoporosis treatment. These differing frequencies highlight why risedronate stands out for its adaptability in treatment regimens while promoting patient compliance.