Which anabolic agent is most commonly used to help with osteoporosis treatment?

• A. Sclerostin Inhibitor
• B. Parathyroid Hormone
• C. Calcitonin
• D. Bone morphogenetic protein

Answer: (B)

Parathyroid hormone is the most commonly used anabolic agent for osteoporosis treatment because it plays a critical role in bone remodeling and stimulates bone formation. This hormone acts by enhancing the activity of osteoblasts, the cells responsible for building bone, while also helping to regulate calcium levels in the blood. When administered as a medication in a synthetic form, such as teriparatide, it has been shown to effectively increase bone mass and reduce the risk of fractures in individuals with osteoporosis.

In contrast, other agents like sclerostin inhibitors, while promising, are not as widely used in clinical practice yet. Calcitonin primarily has a role in pain management and minor effects on bone density and fracturing, rather than acting as an effective anabolic agent. Bone morphogenetic proteins are used more in surgical settings and have not been established as a standard treatment for osteoporosis in everyday clinical use.