What is the brand name of the Sclerostin inhibitor used to stimulate osteoblastic formation?

• A. Forteo
• B. Evenity
• C. Tymlos
• D. Prolia

Answer: (B)

Evenity is the brand name of the Sclerostin inhibitor used to stimulate osteoblastic formation. Sclerostin is a protein produced by osteocytes that inhibits bone formation, and by blocking its action, Evenity promotes the activity of osteoblasts, the cells responsible for bone formation. This mechanism is particularly beneficial in conditions like osteoporosis, where increased bone mass is desired.

In contrast, Forteo and Tymlos are both formulations of teriparatide, a parathyroid hormone analog that also stimulates bone formation but works through a different mechanism. Prolia, on the other hand, is denosumab, which is a RANKL inhibitor that decreases bone resorption rather than directly stimulating bone formation. Understanding these distinct mechanisms highlights why Evenity is specifically classified as a Sclerostin inhibitor, making it the correct answer for the question regarding the stimulation of osteoblastic formation.