What is a characteristic of Turner's Syndrome related to bone health?

• A. Presence of an additional X chromosome
• B. Missing X chromosome in females
• C. Occurs in both genders
• D. High genetic predisposition to osteoporosis

Answer: (B)

Turner's Syndrome is a genetic condition that occurs in females who are missing all or part of one of their X chromosomes. This chromosomal abnormality can significantly impact various aspects of health, including bone health. One of the well-documented effects of Turner’s Syndrome is reduced bone density, which is crucial to note for bone densitometry.

The absence of a complete second X chromosome can lead to a deficiency in estrogen production. Since estrogen plays a critical role in bone health by promoting bone density and regulating bone resorption, its deficiency can lead to an increased risk for osteoporosis and fractures later in life.

This link to a missing X chromosome underlines the need for individuals with Turner's Syndrome to be monitored for bone health issues proactively and to consider preventative measures or treatments aimed at maintaining bone density. In summary, the key characteristic of Turner's Syndrome in relation to bone health is the missing X chromosome, which contributes significantly to the increased risk of osteoporosis in affected individuals.