Type 1 Primary Osteoporosis primarily involves which type of bone?

• A. More cortical bone
• B. More trabecular bone
• C. Equal amounts of both
• D. Bone marrow only

Answer: (B)

Type 1 Primary Osteoporosis predominantly affects trabecular bone. Trabecular bone, also known as cancellous bone, has a spongy or lattice-like structure and is primarily found in the interior of bones, particularly in the vertebrae, pelvis, and long bone ends. This type of bone is particularly susceptible to changes in bone density because of its higher surface area and metabolic activity compared to cortical bone, which is denser and forms the outer shell of bones.

In Type 1 Primary Osteoporosis, which is typically associated with postmenopausal women due to estrogen deficiency, there is an increased rate of bone resorption leading to a loss of trabecular bone. This results in reduced bone strength and an increased risk for fractures, particularly in areas such as the spine and hip. Understanding the distinction between trabecular and cortical bone is crucial in grasping how osteoporosis affects individuals and the mechanisms behind bone health and pathology.