How do antacids containing aluminum affect osteoporosis?

• A. They promote calcium absorption
• B. They inhibit phosphorus absorption
• C. They increase vitamin D synthesis
• D. They have no effect on osteoporosis

Answer: (B)

Antacids containing aluminum primarily work by neutralizing stomach acid, which can influence mineral absorption in the gastrointestinal tract. One of the notable effects of aluminum is its capacity to bind with phosphorus. When aluminum binds with phosphorus, it reduces the availability of phosphorus for absorption in the intestines.

Phosphorus plays a critical role in bone health alongside calcium and vitamin D. A deficiency in phosphorus can lead to decreased bone mineralization, which may exacerbate conditions such as osteoporosis. Therefore, the inhibition of phosphorus absorption by aluminum-containing antacids can contribute negatively toward maintaining optimal bone density.

Understanding this relationship highlights the importance of monitoring the use of aluminum-based antacids, particularly in individuals with existing bone health issues. Maintaining adequate levels of both calcium and phosphorus is crucial for bone integrity, and any factor that disrupts this balance can have implications for the development or progression of osteoporosis.