From which type of cells are markers of bone formation released?

• A. Osteoclasts
• B. Chondrocytes
• C. Osteoblasts
• D. Fibroblasts

Answer: (C)

Markers of bone formation are specifically associated with osteoblasts, which are the cells responsible for the synthesis and mineralization of bone. Osteoblasts play a crucial role in the remodeling of bone tissue by producing various proteins, including osteocalcin and bone morphogenetic proteins, which serve as markers that reflect the activity levels of bone formation.

Osteoclasts, on the other hand, are involved in bone resorption, breaking down bone tissue rather than forming it. Chondrocytes primarily contribute to the formation and maintenance of cartilage rather than bone, while fibroblasts are involved in connective tissue production but do not have a direct role in bone formation. Thus, the presence of markers indicating bone formation is closely linked to osteoblast activity, making this the correct answer.