An increase in overall bone mass is closely related to an accelerated rate of bone ___________ and reduced amount of ____________.

• A. formation; mineralization
• B. formation; resorption
• C. remodeling; formation
• D. resorption; formation

Answer: (B)

An increase in overall bone mass is closely related to an accelerated rate of bone formation and a reduced amount of resorption. Bone mass is maintained and increased through a balance between the processes of bone formation (osteogenesis) and bone resorption (osteoclastic activity). When bone formation exceeds bone resorption, the result is a net gain in bone density, leading to higher bone mass. This principle is crucial for maintaining healthy bones and is particularly relevant in the context of conditions such as osteoporosis, where increased resorption leads to decreased bone mass.

In this scenario, a higher rate of bone formation ensures that more new bone tissue is created, while a reduction in resorption means that less existing bone is broken down. The balance between these processes is essential for overall bone health and density.

In contrast, other options suggest relationships that do not align with the physiological understanding of bone dynamics. For example, linking bone formation with increased resorption contradicts the necessary balance needed for bone mass increase.